Mild cognitive impairment: pathology and mechanisms
نویسندگان
چکیده
منابع مشابه
Mild Cognitive Impairment.
PURPOSE OF REVIEW As individuals age, the quality of cognitive function becomes an increasingly important topic. The concept of mild cognitive impairment (MCI) has evolved over the past 2 decades to represent a state of cognitive function between that seen in normal aging and dementia. As such, it is important for health care providers to be aware of the condition and place it in the appropriat...
متن کاملMild Cognitive Impairment
Cognitive aging has positive and negative effects on mental abilities. With time and experience, we gain new knowledge and skills. We become wiser. However, for most adults cognitive aging also brings slower mental processing, reduced mental flexibility, increased susceptibility to distraction, and more difficulty learning new things. As an example, the amount of detail recalled from a short st...
متن کاملMild Cognitive Impairment
It is estimated that up to one third of adults will experience a gradual decline in cognitive function known as mild cognitive impairment as they age (Low LF et al 2004; Busse A et al 2003). Less severe than dementia, mild cognitive impairment is defined as cognitive defects that do not interfere with daily living. It may include slower thinking, a reduced ability to learn, and impaired memory....
متن کاملDifferent mechanisms of episodic memory failure in mild cognitive impairment.
Mild cognitive impairment (MCI), defined as episodic memory impairment beyond what is expected in normal aging, is often associated with hippocampal atrophy (HA) and may represent incipient Alzheimer's disease. However, recent studies suggest that MCI is very heterogeneous and multiple etiologies likely exist. One possibility is small vessel cerebrovascular disease (CVD). Specifically, we hypot...
متن کاملSleep and mild cognitive impairment
Older adults frequently suffer from sleep disturbances. In addition, with increasing age such disturbances may accompany mild cognitive changes that are symptomatic of a range of neurodegenerative conditions. There is increasing evidence that sleep may represent a prodromal symptom, risk factor or agitator of further decline in cognitive functioning of the older adult. Current research is focus...
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ژورنال
عنوان ژورنال: Acta Neuropathologica
سال: 2011
ISSN: 0001-6322,1432-0533
DOI: 10.1007/s00401-011-0884-1